Its core functions include:
Personnel protection: prevent operators from being exposed to harmful substances and ensure occupational health and safety.
Environmental protection: prevent harmful substances from leaking into the external environment and reduce the risk of contamination.
Process control: handle highly active or highly allergenic materials in a controlled environment to ensure process stability.
Main types:
According to the application scenario and design goals, negative pressure isolators can be divided into:
Laboratory negative pressure isolators: used for highly active drug research and development, microbial experiments or radioactive material handling.
Production negative pressure isolators: used for weighing, packaging, mixing and other processes of highly active APIs (APIs).
Multifunctional negative pressure isolators: combined with sterile and closed functions, suitable for complex process requirements (such as the production of cell therapy products).
Application scenarios:
Highly active drug production: weighing, packaging and mixing of anti-tumor drugs and hormone raw materials.
Laboratory research: experimental operation of highly active compounds, pathogenic microorganisms or radioactive materials.
Biosafety: pathogen handling in biosafety level 3 (BSL-3) or level 4 (BSL-4) laboratories.
Radioactive material handling: production and testing of nuclear medicine or radioactive drugs.
Performance and features:
- High protection level:up to the highest OEB 5 (OEL<1ug/m³);
- Professional customization:according to different process requirements (explosion-proof function is optional), we provide the most suitable isolator design and complete MOCK-UP early in the design and three-dimensional display in the middle of a project.
- Intelligent:intelligent control system, a number of expansion ports, such as printing, storage, etc., and can be integrated into SCADA system;
- Perfect WIP system:the bottom of the chamber is designed to be inclined and the internal arc angle R≥20, without hard-to-clean places;
- Automatic regulation and emergency system:when leakage occurs, the isolator automatically gives an alarm and adjusts the fan frequency to ensure that the air speed of crack is greater than 0.5m/s.
- Various material transfer: configurable RTP (Rapid transfer ports) and online waste discharge port (bagging system);
- Safe filter replacement: PUSH-PUSH filters of the air handling system can be replaced safely to protect personnel’s safety.
- Real-time monitoring of door status:it can monitor the door opening online and continuously monitor the inflatable sealing of the door;
- CDCV service: sterilization cycle development, validation studies and services;
- High-quality manufacturing materials: the inner chamber is made of 316L or PTFE, and the chamber polishing grade is 0.4μm~0.6μm; the brands of all key components are international first-class such as Camfil, EBM, SIEMENS, etc.